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The
Chemistry of Life Extension
50,000 peer reviewed scientific studies
and 5 decades of research conclude that single carbon transfers
are essential to health, well-being, and longevity.
This may be as expected, as the most
basic building block of organic chemistry is the transfer
of single carbon groups. From building the bases of DNA
to putting the final touches on complex protein structures,
single carbon transfers are the brick and mortar of organic
chemistry.
The simplest organic molecule contains
a single carbon surrounded by 4 atoms of hydrogen. Called
methane, it has the shape of a perfect 4-sided pyramid called
a tetrahedron. In this structure, the carbon is in the very
center of the pyramid shape and a hydrogen atom occupies
each of the 4 corners.
If a hydrogen atom is removed from
one corner of the methane pyramid, the carbon atom in the
center can now bond with another atom. The chemical group
just formed - with a carbon and three hydrogen atoms - is
called a methyl group. This is the most fundamental organic
group, without which life as we know it would be impossible.
One of the most important methyl
group transfers in the body is onto DNA itself. Of the 4
DNA bases, only one base — cytosine — is the recipient
of methyl groups (on the number 5 position of its ring structure
to make it 5-methyl-cytosine). The process of adding a methyl
group to a molecule is called methylation; removing a methyl
group is called demethylation; restoring a methyl group
that has been removed to its biologically desirable location
is termed remethylation.
When a human ovum is fertilized,
an enormously complex task of development and differentiation
ensues to give rise to an infant with a multitude of different
cells and tissues. The body uses methyl groups as anchors
on the DNA itself to organize the function of every type
of cell. Attaching to the DNA base cytosine, the specific
pattern of DNA methylation is unique for every cell. The
DNA methylation pattern tells each cell what part of the
DNA can be active and which should be dormant.
When an infant is born, the methylation
of cytosine ranges from 2-6%, the fraction dependent on
the unique pattern for each cell type. This pattern is like
a fingerprint for each cell and gives the cell a blueprint
for which proteins and enzymes and activities it will carry
into function.
Using an estimated average of 3%
methylation of cytosine at birth, the nuclear DNA of each
cell would have approximately 90 million methyl groups.
As reviewed by a recent article in the journal Medical Hypothesis
(Vol. 51, pages 179-221, 1998), the body controls development
and aging by the loss of methyl groups from DNA. Death from
degenerative causes usually occurs when about 40% of the
methyl groups have been lost from DNA.
Cellular information and control
systems become increasingly fuzzy as DNA methyl groups are
lost. Certain cancers tend to occur at a 20% DNA methyl
group loss. In autoimmune diseases like lupus and rheumatoid
arthritis, a specific immune cell called the lymphocyte
has been shown to lose 50% of its DNA methyl groups. Loss
of information integrity in this powerful type of immune
cell causes an attack of self against self, as lymphocytes
attack otherwise normal, healthy tissues.
An average loss of roughly 36 million
DNA methyl groups per cell represents a limit to biological
survival. An average loss of 1800 DNA methyl groups per
cell per day limits a lifespan to about 60-65 years, whereas
a reduced loss to only 1200 groups per cell per day is consistent
with survival to age 90-95.
Factors that accelerate methyl group
loss are smoking, excessive alcohol intake, vitamin deficiencies,
synthetic female hormones, and lack of adequate exercise.
Gematria Products new formula, Heart
Gems, is a state of the art formula that has the full array
of nutrients proven to enhance and restore methyl group
transfers. The main driver of supplying methyl groups is
called trimethylglycine, an amino acid that offers three
extra methyl groups per molecule. Also called betaine, this
is a safe and natural product derived from sugar beets.
Heart Gems has 10 different validated
vitamins, minerals, and methyl group suppliers to boost
methyl metabolism strongly in each and every cell. Just
providing one of these factors has been associated with
a 7-17 year life extension and 75% reduction in cardiac
disease compared to those not thus supplemented.
Beyond providing nutrients that have
been proven to be required for optimum methyl group transfers,
Heart Gems is further enhanced with a patented process for
increasing nutrient potency. Using an advanced modulated
wave of laser light, the methyl groups of the methyl donors
in Heart Gems are stimulated to increase their biologic
activity and potency.
Each 3 capsule serving of Heart Gems
provides every cell in the body with 50 million methyl groups.
This gives each cell a great surplus of methyl groups to
slow and reverse the loss of these life-preserving groups
from DNA. Methyl groups not used to remethylate DNA can
participate in a wide range of highly beneficial functions
such as the following:
- Building the bases of DNA itself.
- Making the myelin sheaths of nerves.
- Rejuvenating proteins that have
degenerated.
- Detoxifying organic poisons.
- Producing chemical messengers
in the brain.
- Reducing risks of heart attacks,
strokes, and cancer.
- Repairing joint cartilage and
relieving joint pain.
- Inactivating histamine to relieve
allergic responses.
- Boosting mood through enhanced
serotonin production.
- Increasing energy, endurance,
and stamina.
- Improving fluidity and repair
of cell membranes.
- Providing essential conditions
for cell regeneration.
Extensive research has shown that
the Heart Gems ingredients are very effective at increasing
SAMe (S-adenosyl-methionine) production in the body. Clinical
studies have shown SAMe to be very powerful at elevating
mood quickly and safely, healing joints, relieving aches
and pains even of fibromyalgia, and preventing and healing
liver damage. SAMe is the specific methyl group donor that
the body uses to restore methyl groups to DNA.
As an indicator of the beneficial
impact of Heart Gems, taking just 3 capsules per day, one
with each meal, has already shown the following results:
- 20-25 point reduction in total
cholesterol.
- 18-25% lowering of the "bad"
LDL cholesterol.
- Preserved HDL level, with reduced
total/HDL ratio.
- 23-27% reduction in homocysteine
(Hcy) levels.
- 30-35% decreases in cardiac risks
just from reduced Hcy.
The recent article in Medical Hypothesis
presents evidence that aging may be almost entirely due
to a loss of methyl groups from DNA, with elevated
homocysteine a marker for impaired methyl group transfers
throughout the body. This study concludes that aging
may be reversible if aged cells could be stimulated to restore
methyl groups to DNA. Heart Gems provides all the necessary
factors required for methyl group transfers to DNA and profound
lowering of homocysteine.
With aging, homocysteine levels tend
to increase, with higher levels in men, smokers, and those
who use coffee and alcohol excessively. The Hordaland study
of 15,000 men and women gives a relationship between age
and homocysteine levels that can be used as a marker for
the physiologic age of the body’s chemical functions.
Based upon measured homocysteine
levels, the chemistry of a young woman shifted from that
of about 35 (near her chronological age) to that of an 18-year-old
in 3 weeks taking 3 capsules of Heart Gems daily. Taking
9 capsules daily, 3 with each meal, another subject had
a reduction in aging chemistry from the mid 60’s to
the mid 20’s — in only 6 weeks.
As further reviewed in Medical Hypothesis
article, the most powerful remethylation of DNA occurs if
the cell environment is rich in antioxidant hormones and
antioxidants. Perhaps the two most potent antioxidant hormones
are cyclic GMP (cyclic guanosine monophosphate) and growth
hormone. A highly safe and proven way to increase these
hormones is through providing supplements of the amino acid
L-arginine, which raises cellular cyclic GMP (through increased
production of nitric oxide, which is also a potent antioxidant)
and directly stimulates natural growth hormone release.
The new product NITROXx provides
the most biologically active L-arginine ever released. Using
a patented laser activation process similar to that used
for Heart Gems, the L-arginine is made significantly more
potent than ordinary L-arginine not thus treated.
Immune cells intensely stimulated
with bacterial toxins increased their nitric oxide production
(a molecule used to eliminate harmful bacteria, viruses,
and cancer cells) 200%. Despite this near maximum stimulation,
when the immune cells were also given activated L-arginine,
nitric oxide production was much further boosted —
to 350% over baseline. This was a highly statistically significant
increase.
NITROXx contains laser enhanced L-arginine
and the cofactors required for optimum use and action of
L-arginine in the body. At 2-4 capsules with each meal,
numerous published studies report a wide range of potential
benefits at this level of ingestion:
- Improved blood supply throughout
the body.
- Reduced risk of heart attacks,
stroke, and gangrene.
- Decreased risk of life-threatening
blood clots.
- Reduced total and "bad"
LDL cholesterol.
- Prevents oxidation of LDL cholesterol,
reducing risk of injury to blood vessels.
- Restored sexual function comparable
to Viagra effects.
- Better long-term memory (requires
nitric oxide).
- Significant anti-cancer effects.
- Marked boost in immune system
function.
- May heal scarring in heart and
blood vessels.
- Powerful antioxidant actions.
- Promotes shift to more alkaline
blood chemistry.
- Stimulation of growth hormone
release.
- Rejuvenation of nearly every tissue
in the body.
A gentleman with very elevated homocysteine
and cholesterol levels — a walking time bomb for a
major vascular event — showed the potency of the new
life extension formulas. He took 6 Heart Gems and 2 NITROXx
with every meal and reduced his aging chemistry from
that of a 90-year-old man to that of a 30 year old in less
than 2 months. The dramatic lowering of his homocysteine
and cholesterol levels reduced his cardiac risks by well
over 80%.
Further benefits can be realized
through eating several servings of fruits and vegetables
daily. Fruits and vegetables provide antioxidants, phytonutrients,
vitamins, minerals, and trace elements that work additively
and synergistically with Heart Gems and NITROXx. For persons
for whom it is not convenient to ingest at least 5-7 daily
servings, the Life Gems formula provides concentrates of
55 different fruits, vegetables, and herbs.
The intake of 1-3 Heart Gems and
2-4 NITROXx with each meal delivers a profound one-two punch
for life extension, life enhancement, and total body tissue
repair. The program is made complete by combining these
formulas with fresh fruits and vegetables, supplemented
with Life Gems as needed. Long-term use of this program
may provide the most powerful synergistic triad for a better,
longer life that has ever been made available.
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